Filter Chemical Compatibility

Does the filter need to be resistant to bases, acids, or organic solvents? Chemical compatibility is a critical consideration when selecting the sample prep syringe filter or mobile phase disc filter for your application. The broad guidelines below can be used for basic information.

Aqueous Samples

Hydrophilic membranes, which have an affinity for water, are preferable when filtering aqueous samples. Use  filters with  PES, Nylon, or PVDF membranes.

Gases and Aggressive Organic Solvents

Hydrophobic membranes repel water and are inert to aggressive organic solvents, making them ideal for gases and organic solvents. Choose filters with PTFE membrane.

HPLC Certified for Low Extractables

Membrane silutions HPLC certification ensures that analytical results will not be compromised by extractable filter materials. Our membranes have been tested for compatibility with common HPLC solvents (water, acetonitrile and methanol) using established HPLC procedures. In addition, to verify low levels of UV-detectable extractables, samples of the entire HPLC Acrodisc syringe filter line are evaluated prior to release.